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Nick Powell could start for Wigan after making his return from a groin injury as a substitute in the Latics’ draw with Fulham on 17 September.
Midfielder Alex Gilbey and defender Reece Burke remain out as Wigan seek a first win in eight league games.
Wolves striker Nouha Dicko will not feature despite making his return from a knee injury in an under-23 team game.
Ivan Cavaleiro could start after coming off the bench to score in the 3-1 victory over Brentford.
- There has never been a goalless draw between these sides in any competition in 16 meetings stretching back to December 1985.
- Wolves won on their last away league trip to the Latics but have never won back-to-back games there.
- Wigan have picked up just one win from their past 11 matches in the second tier (D2 L8).
- Wolves have kept just one clean sheet in their past 12 away league games, although it came last time out on the road.