Club captain Leon Britton also played in that fixture and is set to return to Premier League action against Leicester after missing the 2-0 defeat by Hull City.
Ecuadorian winger Jefferson Montero is also vying for a start, but the Swans will again be without new £15m record signing Borja Baston because of injury.
Borja has yet to feature since his arrival from Atletico Madrid but is likely to play after the international break.
Oliver McBurnie, 20, scored twice on his debut against Peterborough, but Guidolin says the Scottish Under-21 international is not yet ready for the rigours of the Premier League even though he will not be loaned out.
“I think he needs to improve. But he is always with us in training and the future is for him,” said Guidolin.
With the transfer window closing on Wednesday night, Guidolin reiterated his priority is to sign another centre-back, following the departure of skipper Ashley Williams to Everton.
“We need another centre-half. I am happy with my three centre-backs but the season is very long, we need another centre back,” he added.
Swansea’s trip to Leicester brings Guidolin face-to-face with fellow Italian Claudio Ranieri, who led the Foxes to their astonishing title success last season.
“I think Leicester could make a good season in the Premier League and a good tournament in the Champions League because the team is strong, with strong players and a very very good manager,” said Guidolin.
“But it’s very difficult to repeat the same result in the Premier League.”
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