Southampton striker Graziano Pelle could return after sitting out last weekend’s win at Aston Villa.
Charlie Austin has returned to training following a hamstring injury and may be included on the bench.
Manchester City playmaker David Silva is out for at least a fortnight after suffering a hamstring injury against Real Madrid in midweek.
Yaya Toure is back in training after a thigh injury but will not be involved, while Samir Nasri is fit and available.
MOTD COMMENTATOR’S NOTES
Simon Brotherton: “Manchester City travel to the south coast with the second leg of their Champions League semi-final against Real Madrid at the Bernabeu looming large on the horizon.
“It’s likely to lead to a few changes to their line up, but a top-four finish isn’t guaranteed yet and they can expect to face a tough afternoon against an in-form Southampton side with plenty to play for.
“Saints have won four of the last six games and are only a couple of points behind West Ham in the race for sixth and the probable Europa League spot that will come with it.”
Southampton manager Ronald Koeman on whether he will manage the club next season: “Yes, of course. I don’t like to talk about individual clubs because I think everybody has ambition, and I have that also, but I signed a three-year contract with Southampton.
“The club makes a five-year plan and of course I’m interested in how we see the plan and discuss about that plan and agree or not. It was good to see they still have ambition to grow and to make the next step.”
Manchester City manager Manuel Pellegrini: “The best way to make a good game on Wednesday (against Real Madrid) is to win on Sunday and have trust in the performance of different players.
“Our mind is the same, to continue trying to win all our games and have a spot in the Champions League for next year, and be as near the top of the table as we can.”
This game comes three days before City’s Champions League semi-final second leg at Real Madrid but I think City will win at St Mary’s because they know they are close to securing a top-four place.