Southampton will have Sadio Mane available after he successfully appealed against the red card he received against Stoke last weekend.
Victory Wanyama could make his first appearance since the start of February after serving a five-match ban.
Liverpool left-back Alberto Moreno will have another scan on the hamstring injury which ruled him out on Thursday but he could be involved.
The visitors are still without suspended midfielder James Milner.
MOTD COMMENTATOR’S NOTES
John Roder: “Liverpool won handsomely at St Mary’s on their last visit to Southampton, in the League Cup back in December, but this encounter is far more likely to mirror the draw at Anfield in the league in October.
“Both teams have an exciting end to the season ahead. Southampton will be looking to improve on last year’s seventh-placed finish in Ronald Koeman’s first season in charge, and have every reason to believe they will do so.
“Liverpool have an enticing Europa League quarter-final to come against Jurgen Klopp’s former side Borussia Dortmund and arrive on the south coast having scored plenty of goals in the last few weeks – Fraser Forster may be in for a busy afternoon in what should be an excellent match.”
Think you can do better than Lawro? Predict the score for this match and the rest of this round’s Premier League fixtures in our Predictor game.
Liverpool won 6-1 on their last visit to St Mary’s in the League Cup earlier this season, while they have also won on their last two Premier League visits.
The Saints haven’t lost three successive Premier League games at home to Liverpool since December 1996.
Southampton have lost just one of their last six Premier League games at St Mary’s (W4, D1), although they have gone two games without a win.
Ronald Koeman’s side have won 20 points from their last 10 games – only Leicester (23) and Tottenham (22) have claimed more.
If Fraser Forster keeps a clean sheet in this match, he’ll be the fourth quickest goalkeeper to reach 20 clean sheets in the Premier League (currently 19 clean sheets in 40 games) after Petr Cech (26), Jose Reina (32) and Roy Carroll (37).
Southampton have scored a league-high 12 headed goals this season.
Liverpool are looking to win four successive Premier League games for the first time since March last year.
They are unbeaten in their last eight matches in all competitions (W5, D3).
They have scored 13 goals in their last four Premier League away games.
Christian Benteke needs one more goal to reach 50 in the Premier League. He has scored in each of his last two league games against Southampton.