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Preston could have Paul Huntington (calf) and Jermaine Beckford (knee) involved again after they both came on as late substitutes in the win against Blackburn on Saturday.
Stevie May, Liam Grimshaw (both knee) and Chris Humphrey (shin) are all out.
Emerson Hyndman could return to the Fulham squad after international duty with the United States.
Defender Chris Baird is doubtful and midfielder Lasse Vigen Christensen remains out with a hamstring injury.
Veteran former England international Scott Parker will be assessed having played the full 90 minutes against MK Dons on Saturday.
- Preston have not kept a clean sheet in their last seven home games against Fulham.
- Fulham have lost just one of their last six contests against PNE (W3 D2).
- Only league leaders Burnley (24) have picked up more points than Preston (20) over their last 10 league games.
- Fulham have scored 27 goals away from home in the league this season; a total which only Burnley can better (28).