The Monday night match will probably come too early for Dimitri Payet – it’s unlikely he’ll start at Stamford Bridge.
The Hammers‘ talisman only appeared for the final quarter of an hour of the friendly against Juventus after being given a break following Euro 2016.
So what is Slaven Bilic’s starting line-up likely to look like? And which new signings will start the game?
Click through the gallery above to see our predicted West Ham line up v Chelsea.