Laurent Koscielny, Olivier Giroud, Mesut Ozil and Aaron Ramsey will need some time off after their scintillating Euro 2016 performances.
Alexis Sanchez picked up an ankle injury while playing for Chile against Argentina in the Copa America final.
The Chilean will need some more time to reach top form.
That means Wenger might have to field a flimsy side against the Reds, based on the Gunners‘ current squad, on August 14.
Find out who could start at the Emirates in our gallery above.