The Championship side will be without injured trio Damien Perquis, Britt Assombalonga and Thomas Lam.
Arsenal boss Arsene Wenger could rotate his squad, with David Ospina, Rob Holding, Kieran Gibbs, Lucas Perez and Chuba Akpom all hoping to feature.
Olivier Giroud (toe) missed Saturday’s win at Hull, but could be available.
Nottingham Forest and Arsenal have met twice before in the League Cup. Both encounters were 2-0 quarter-final home victories for the Gunners, in 1987 and 1993, with Arsenal going on to win the trophy both times.
Arsenal have won their last three matches against Nottingham Forest, beating them in the Premier League in 1997, 1998 and 1999.
In fact, Forest have only won one of the last 13 meetings against Arsenal in all competitions (D4 L8).
Arsenal were eliminated when they last faced Championship opponents in the League Cup, losing 3-0 at Sheffield Wednesday last season.
Forest have lost their last nine League Cup games against Premier League opponents (as a lower ranked side), last beating Manchester City in December 1993.