Manchester United will be without the suspended Juan Mata but Jesse Lingard is available after a European ban.
Wayne Rooney, Luke Shaw and Ashley Young are among the club’s long-term absentees.
West Ham have Enner Valencia, Victor Moses and Joey O’Brien available following injury lay-offs.
Winston Reid could also return, but fellow defenders James Tomkins and James Collins are injured and Sam Byram is cup-tied.
MOTD COMMENTATOR’S NOTES
Steve Wilson: “It wasn’t just losing, it was the manner of their defeat at Liverpool which would have stung the travelling Manchester United fans, which included Gary Pallister, Andy Cole and Denis Irwin. Who knows what Sir Alex made of it from the posh seats?
“United could yet progress past Liverpool, they could yet finish in the top four, but the feeling that neither is likely makes this cup tie against West Ham all the more important.
“The Hammers couldn’t be happier. They have won their last four games, and made ridiculous the notion that staying in the Premier League was their season-goal before moving to Stratford with a thrilling combination of adventure and skill.”
WHAT THE MANAGERS SAY
West Ham manager Slaven Bilic: “They are like a wounded lion, they have a massive game against us. It’s going to be very difficult but are we confident? Yes of course we are confident, but not because Manchester United didn’t play well (against Liverpool). We are confident because we are playing well.
“But it would be dangerous, suicidal, if we approach the game like ‘they are playing badly, we are playing well, and we are going to cruise it’. No way we will do that.”
This is going to be a tough one for Manchester United.
The Hammers do not let teams bully them away from home and they are great at coming from behind in games. They can take the tie back to Upton Park – and I fancy them to win it there.
Prediction: 1-1 (West Ham to win the replay)
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- The two sides last met in the FA Cup three seasons ago, with Manchester United securing a 1-0 home victory in a third-round replay.
- The Hammers are winless in their last nine trips to Old Trafford in all competitions (D1, L8).
- West Ham’s last two cup triumphs over United were at Old Trafford, the most recent being by 1-0 in 2001.
- The 11-time FA Cup winners last lifted the trophy in 2004.
- They have lost both of their last two sixth-round appearances, including a 2-1 home defeat by eventual winners Arsenal last season.
- United have conceded only once in their three previous FA Cup games this campaign.
- They have scored 12 goals in their last four games at Old Trafford in all competitions, as many as they had managed in their previous 13 home matches.
West Ham United
- Three-time winners West Ham have not won the FA Cup since 1980,
- They last reached the final a decade ago, losing on penalties to Liverpool.
- West Ham have won 10 of their last 15 games in all competitions (D3, L2).
- The Hammers have scored seven goals in their last two FA Cup ties.
- They last reached the sixth round in 2010-11 season, where they were eliminated 2-1 at Stoke.
- Michail Antonio has scored in his last three appearances in all competitions.