A 28-year-old man has been arrested by detectives investigating the attack on the Manchester United team bus before Tuesday’s clash.
The suspect handed himself in to an east London police station on Friday and was arrested on suspicion of violent disorder.
He was bailed to a date in mid-August, pending further inquiries.
Commander BJ Harrington of the Met’s Public Order team said: “Behaviour of the kind we saw before Tuesday’s match is totally unacceptable. The vast majority of people were well behaved, but we are looking to deal with a small minority of individuals who committed criminal acts.
“We are working closely with both clubs to bring these individuals to justice, and I would urge anyone who recognises the men in these pictures to contact police.
“This was always going to be a challenging match to police, with passions running high. Aware of those challenges, we had more officers on duty than is normal. I am proud of my officers who did a fantastic job in difficult circumstances and played their part in enabling those supporters who respected the occasion to enjoy what was an historic event.”
Bottles and other objects were thrown at the coach as it made its way to Upton Park.
Video footage posted online appeared to show the Manchester United players, including Jesse Lingard and Michael Carrick, cowering in mock fear as missiles pelted the windows.
Police have also arrested three other men in connection with disorder both inside and outside the ground.
Two men, aged 18 and 47, who were arrested for pitch incursion have been bailed to return on a date in late May.
A 20-year-old man arrested for affray – throwing bottles at police officers – was bailed to return on a date in August.