Lallana started in a strong Reds line-up, alongside Danny Ings, Dominic Solanke and Ben Woodburn.
Discussing Lallana last week, Klopp said: “It’s really unlucky. It was a really serious injury in the summer.
“Because of Adam’s quality and attitude in training, it looks immediately like we can put him in, but physical-wise he’s not fit.
“The two things that happened after his big injury were in the 10 or 15 minutes after he came on. From nil to 100 in a second, and that’s maybe what caused the problem.