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Hull midfielder Jake Livermore is set to return after being rested for Tuesday’s 2-1 win at Reading.
Manager Steve Bruce must decide whether to stick with David Meyler and Tom Huddlestone in central midfield.
Leeds midfielder Tom Adeyemi (illness) and winger Mustapha Carayol (hamstring) are not expected to feature.
Midfielder Lewie Coyle and striker Lee Erwin started on Tuesday night but could make way for Stuart Dallas and Mirco Antenucci.
Hull have not conceded a goal in their past two home games against Leeds (W1 D1) and a third clean sheet would be their longest run against United.
Leeds’ only win in five trips to the KC Stadium came in January 2007 thanks to goals from Matt Heath and Alan Thompson in a 2-1 victory.
Only Middlesbrough (7) have conceded fewer goals than Hull (9) at home in the Championship this season.
Leeds have won their past three games and six of their past 10 (D1 L3).
Hull have lost only one of their previous 21 home league games and are unbeaten in their past 11 (W7 D4).