Southampton earned a valuable Europa League point against Hapoel Be’er-Sheeva from a dour affair in Israel.
Saints did not have a shot on target in the first half – Virgil van Dijk heading way wide when unmarked inside the six-yard box.
The game improved after the break, James Ward-Prowse forcing a save from long range and Maor Melikson and Ben Sahar each going close for the hosts.
Southampton and Hapoel are level on four points at the top of Group K.
They are one ahead of Sparta Prague, who inflicted a second defeat on Inter Milan after the Italian giants lost their opener 2-0 at home to Hapoel.
That Hapoel have already won in the San Siro and are unbeaten in 23 games at their new Turner Stadium makes this a worthy point for a Southampton side who had won their previous four and made seven changes from the Premier League victory at West Ham.
However, it was not a great spectacle for the 300 Saints fans who made the 3,000-mile journey to the Israeli champions.
After Van Dijk nearly hit the corner flag when it seemed easier to hit the target, Hapoel dominated the first half, forcing Southampton boss Claude Puel to withdraw 19-year-old Jake Hesketh if favour of Dusan Tadic after only 33 minutes.
Still, the home side forced no clear chances of note, meaning the game could improve in the second period.
With Saints showing more intent, Ward-Prowse cut in from the left to shoot low and call home keeper David Goresh into action.
However, it was Hapoel who came closest to finding a winner. The impressive Melikson shot wide from inside the box, former Chelsea man Sahar fired off target from outside the box when given a clear sight of goal and Ovidiu Hoban forced Fraser Forster into a smart save.
But the deadlock remained unbroken, with Southampton facing a long journey home before a Premier League trip to Leicester City on Sunday (14:15 BST).
Match ends, Hapoel Be’er Sheva 0, Southampton 0.
Second Half ends, Hapoel Be’er Sheva 0, Southampton 0.
Attempt blocked. Ovidiu Hoban (Hapoel Be’er Sheva) right footed shot from outside the box is blocked. Assisted by John Ogu.
Attempt blocked. Dusan Tadic (Southampton) right footed shot from the right side of the box is blocked.
Ben Sahar (Hapoel Be’er Sheva) is shown the yellow card for a bad foul.
Foul by Ben Sahar (Hapoel Be’er Sheva).
Maya Yoshida (Southampton) wins a free kick in the defensive half.