Manchester United, Tottenham and Liverpool all await Friday’s Europa League round of 16 draw – with an all-English tie a possibility.
Spanish side Valencia, managed by ex-United defender Gary Neville, are also in the draw which takes place in Switzerland at about 12:00 GMT.
Holders Sevilla and German giants Borussia Dortmund are among the favourites to win the competition.
There are no seedings or restrictions on facing sides from your own country.
The last-16 ties will be played on 10 and 17 March.
The final takes place at Basel’s St Jakob-Park on Wednesday, 18 May.
Who else is through?
Valencia coasted into the last 16 as they thrashed Austrian hosts Rapid Vienna 4-0 to complete a 10-0 aggregate win.
Fellow Spanish outfit Sevilla, who have won the Europa League for the past two seasons, lost 1-0 at Norwegian side Molde but eased through 3-1 on aggregate.
Bundesliga runners-up Dortmund progressed as Porto goalkeeper Iker Casillas’s own goal, after Pierre-Emerick Aubameyang’s shot hit the crossbar, sealed a 3-0 aggregate win for the Germans.
Swiss champions Basel are still on course to reach a ‘home’ final after a dramatic injury-time win against French side St Etienne.
Luca Zuffi scored a late goal for a 2-1 win on the night, sending Basel through on away goals after the tie finished 4-4.
Italian title chasers Napoli were eliminated after a 1-1 home draw against Villarreal put the Spanish team through 2-1.