Last season’s beaten finalists Liverpool will face Derby away after a 5-0 thrashing of Burton Albion secured their place in the third round.
Meanwhile, 2015/16 winners Manchester City are set to take on Swansea in Pep Guardiola’s first ever taste of the competition.
Jose Mourinho, a three-time EFL Cup champion during his two spells with Chelsea, will lead new club Manchester United against Northampton.
Arsenal boss Arsene Wenger will begin the quest for his maiden League Cup glory away to Nottingham Forest.
Elsewhere, new Stamford Bridge supremo Antonio Conte is poised to take his Chelsea side to Leicester, after Tuesday’s night’s 3-2 win over Bristol Rovers.