Ryan Bertrand misses out again as Claude Puel takes his Southampton squad to face Manchester United at Old Trafford on Friday night.
The England international was sidelined for Saints’ 1-1 draw with Watford last weekend and is still not ready to return.
Matt Targett is set to continue at left-back but there could be a change in central defence with Puel weighing up whether to start skipper Jose Fonte alongside Virgil van Dijk.
Saints have no fresh injury concerns with summer signings Pierre-Emil Hojbjerg and Jeremy Pied pushing for further action after coming off the bench at St Mary’s last week.
Southampton (from): Forster, Van Dijk, Fonte, Yoshida, Soares, Targett, Clasie, Davis, Ward-Prowse, Romeu, Tadic, Long, Austin, Pied, Rodriguez, Hojbjerg, McCarthy, Redmond.