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Tottenham striker Harry Kane remains sidelined with an ankle injury for the side’s Champions League group game at CSKA Moscow on Tuesday.
Spurs will also be missing left-back Danny Rose and midfielders Eric Dier, Mousa Dembele and Moussa Sissoko.
Dier, Rose and Dembele are absent with hamstring injuries.
Sissoko suffered concussion in a league win at Middlesbrough on Saturday and is also out as Spurs try to recover from an opening Group E defeat by Monaco.
“The Champions League is a new competition for us and it’s important to have a strong squad for it,” said manager Mauricio Pochettino.
“We’ve signed several strong players to increase the competition in the team and now despite the injuries we’re still a competitive side.”
Spurs are second in the Premier League but after the defeat against Monaco, the Argentine is keen for his team to pick up their first European points.
“Now we need to improve our performance, we need to win on Tuesday,” he added.
“It’s very important to get all three points. We know it will be a very tough game but in our minds we want to get three points.”
No danger for fans, says CSKA boss
Tuesday’s match will be the first trip to Russia by a side from England since Euro 2016, when the group fixture between the two nations was marred by violence.
CSKA manager Leonid Slutsky, in charge of Russia in France, is confident there will be no problems in Moscow.
“I believe that those English fans who come to Moscow to support their favourites will enjoy a high level of hospitality, not only at the stadium but everywhere,” said Slutsky.
“I’m confident that they’re in no danger. They have no reasons for fears.”