The Eagles have won six of their last 11 meetings with the Reds in all competitions, but are struggling for form in the Premier League having not picked up three points since their 2-1 victory over Stoke City at the end of December.
Liverpool, meanwhile, immediately bounced back from their League Cup heartbreak, dispatching three past the same opponents, Manchester City, and will be looking to kick on to close the gap on the top four.
Both sides have their injury problems with Lucas unavailable for the visitors for five to six weeks after suffering a thigh strain in the League Cup loss. Daniel Sturridge, Mamadou Sakho and Philippe Coutinho could return, however.
Alan Pardew could be without Connor Wickham and Wayne Hennessey, while James McArthur and Jason Puncheon have been ruled out.
And the teams have now been confirmed ahead of kick off.
Crystal Palace XI: McCarthy; Ward, Dann, Delaney, Souare; Zaha, Jedinak, Cabaye, Ledley, Bolasie; Adebayor
Subs: Speroni, Kelly, Lee, Mutch, Sako, Chamakh, Gayle
Liverpool XI: Mignolet, Flanagan, Lovren, Sakho, Moreno, Henderson, Can, Milner, Lallana, Firmino, Origi
Subs: Ward, Toure, Clyne, Allen, Coutinho, Sturridge, Benteke