Burnley forward Andre Gray serves the second game of a four-match ban for comments he made on Twitter in 2012.
Manager Sean Dyche could keep faith with the side which secured a 2-0 win over Watford on Monday night.
Arsenal will assess the fitness of midfielder Francis Coquelin, who has recovered quicker than expected from a knee injury.
Olivier Giroud, Aaron Ramsey, Per Mertesacker, Danny Welbeck and Carl Jenkinson remain sidelined.
MOTD COMMENTATOR’S NOTES
Guy Mowbray: “Arsene Wenger has huge respect, and maybe even a soft spot, for Burnley.
“After his last visit to Turf Moor, a 1-0 Gunners win in April last year, he praised Sean Dyche’s team and said it ‘would be a shame if they go down’.
“I suspect the sentiments remain the same today, with the Clarets’ economic prudence perhaps contributing to his admiration.
“They’ve been a little more extravagant for this latest return to the Premier League, breaking their transfer record twice in August, but Monday’s win over Watford showed that they’ve spent wisely on Jeff Hendrick and Steven Defour.
“Defour’s superb set-piece delivery gives them much more of a chance in games like this.”
WHAT THE MANAGERS SAY
Burnley manager Sean Dyche on Arsene Wenger: “Arsene, for me, is one of the top managers without a shadow of a doubt.
“A lot of respect goes out from me, as a young manager, looking at him and what he’s done… the way he puts a team together, the style, the manner.
“As managers we all understand the fan mentality, the thirst and desire to win and be successful, but from a manager’s point of view you have to scratch your head and wonder why he’s questioned at times.”
Arsenal manager Wenger on his 20 years in charge: “A lot has changed. The art of management has changed, the club has grown bigger, it is now a global club. Twenty years ago it wasn’t as big, or as expensive.
“Football has become popular, it’s become a world sport. Everything has changed and the pressure has intensified too.
“But what hasn’t changed is the solidarity inside the club. That’s always stayed the same.”
I like the look of Arsenal at the moment – they were very comfortable in their wins against Chelsea and Basel.
They will have to match Burnley’s work ethic but, if they do that, I think the Gunners will make it five wins in a row in all competitions.
- Think you can do better than Lawro? Predict the score for this match and the rest of this round’s Premier League fixtures in our Predictor game
- Burnley are winless in seven league meetings since 1974, including all four Premier League fixtures (D1, L3).
- However, the Clarets did win 2-0 at home in a League Cup fifth-round tie in December 2008.
- The last three league meetings between the two sides at Turf Moor have produced just three goals, one for Burnley and two for Arsenal.
- Sean Dyche’s side have conceded just five goals in their last 17 home league fixtures, and never more than once in a match during that period.
- However, Burnley have only managed 15 shots on target in their six Premier League games this season – only Middlesbrough, with 12, have a worse record.
- Steven Defour has been directly involved in four of Burnley’s five Premier League goals this season, scoring one and setting up three.
- Tom Heaton has made a league-high 30 saves after six rounds of matches.
- Arsenal have won four successive league games and lost just one of their last 16 matches in the division (W9, D6).
- The Gunners are unbeaten in their last 26 Premier League fixtures against promoted teams, winning 22 and drawing four since a 2-1 defeat at QPR in March 2012.
- Theo Walcott has registered a goal in consecutive Premier League games for the first time since a three-match scoring run in May 2013.
- Full-back Hector Bellerin has provided six assists in the Premier League since the start of last season, more than any other defender.
- Alexis Sanchez has scored three goals in as many games against Burnley.
SAM (Sports Analytics Machine) is a super-computer created by @ProfIanMcHale at the University of Salford that is used to predict the outcome of football matches.