Full-back Pisano injured his hamstring during the 2-0 win at Fulham on what was his first start in the Sky Bet Championship for two months.
Central defender Baker missed Tuesday’s game at Craven Cottage with a knee injury picked up at Sunderland last weekend.
Loan striker Cauley Woodrow returns to the squad after being unable to face his parent club Fulham.
Joe Bennett will be absent again for Cardiff after missing the 3-1 win over Ipswich in midweek.
So Lee Peltier switches over to left-back with Callum Paterson on the opposite flank.
Kenneth Zohore and Aron Gunnarsson face fitness tests on ankle injuries, with Anthony Pilkington ruled out by a dead leg.
Matthew Connolly is set to return to the squad after an ankle problem.