BBC local radio; live text commentary on the BBC Sport website
Brentford will check on midfielder Lewis Macleod (knee), while Andreas Bjelland could return to the defence.
Goalkeeper Jack Bonham and defender Yoann Barbet (ankle) are out, and midfielders Alan McCormack (heel) and Alan Judge (knee) are also sidelined.
Sheffield Wednesday remain without injured trio Jose Semedo, Glenn Loovens and Marco Matias.
Former Burnley midfielder David Jones could start after making his debut from the bench in the Owls’ defeat by Leeds.
BBC Radio London’s Billy Reeves: “Brentford gaffer Dean Smith has been busy dismissing suitors for injured star man Alan Judge and striker Scott Hogan, who returned from long-term injury earlier this year.
“Smith has also been defending his side’s controversial free-kick routine, in which two or three players stand a few yards from the opposition goalkeeper to upset the planning of the defensive wall.
“That aside, Brentford have won their two home games and lost two away. With no new injury worries the Bees take on one of the pre-season favourites in Sheffield Wednesday, who will attempt to turn midfield into a proper scrap.”
Brentford haven’t won any of their last six league games against Sheffield Wednesday (D2 L4).
The Owls have lost only one of their last 10 trips to the Bees in all competitions, winning five and drawing four.
Scott Hogan has netted eight goals in his last eight league appearances for Brentford.
The Owls have lost consecutive league games for the first time since September 2015; they last lost three in a row in May 2014.
Brentford are unbeaten in their last six league games at Griffin Park, winning five (D1).
Sheffield Wednesday have scored just two goals in their opening four games; their lowest return at this stage of the season since 2005-06.