Scott Hogan scored a hat-trick as Brentford grabbed four goals in the last 15 minutes to thrash Preston.
The striker broke free of the visiting defence for his first, showing composure to find the bottom corner.
Eoin Doyle’s flick was tipped on to the post for Preston, but Harlee Dean drove home a second and Marnick Vermijl’s injury meant Preston ended with 10 men.
That allowed Hogan to round the keeper to net his second, and he completed his treble after Chris Humphrey’s own goal.
Brentford’s victory lifts them into the play-off positions, while the Lilywhites are now only a point above the bottom three.
Humphrey’s own goal came from a Joshua Clarke cross – his attempted clearance going into the net.
Meanwhile, Hogan, who now has 13 goals in 16 Championship appearances for the Bees, completed his treble after running into the channel and striking into the top corner.
Dean Smith’s side are now unbeaten at Griffin Park in eight games and have beaten Preston on their last six visits.