Bournemouth pair Joshua King and Harry Arter are doubts because of respective calf and Achilles problems.
Tyrone Mings – already out for the rest of the season – could miss the start of 2016-17 following a setback in his recovery from a long-term knee injury.
Fabian Delph, Joe Hart, Vincent Kompany, Raheem Sterling and Yaya Toure are all unavailable through injury.
Kevin De Bruyne and Samir Nasri return after lengthy absences, although both are lacking in match fitness.
MOTD COMMENTATOR’S NOTES
Simon Brotherton: “The outcome here partly depends on which Manchester City turn up. If it’s the one we’ve seen in recent weeks, then Bournemouth will fancy their chances. They’ll be mindful of what their opponents are capable of though after losing 5-1 at the Etihad in October.
“With four defeats in the last six games, City’s title challenge has unravelled and their top four place is now seriously under threat. West Ham and Manchester United are just a point behind, with Southampton only four points back.
“A return to some sort of form is needed sooner rather than later if they’re not to miss out on the minimum expectation of Champions League football next season under Pep Guardiola.”
Bournemouth manager Eddie Howe: “We have moved on [since losing 5-1 at Manchester City in October]. That game was a difficult one for us. We conceded very early and when you go away it does make it more difficult.
“The key thing is we learned from that and we have become a better team for the experience.
“I still feel the players are confident despite the Tottenham game, which was a really disappointing performance.
“We still feel as though we need results and points. I don’t think we can afford to step off, and we will try and deliver.”
Manchester City manager Manuel Pellegrini: “We’re disappointed because one month ago we were involved in all the competitions, just three points behind the leaders.
“We have to play another eight games – it’s not in this moment a bad season, we won a title [the League Cup], we’re still in the Champions League.
“We were forced to leave the FA Cup because we had so many games and unfortunately we had a bad performance in the last game. It’s not the time to analyse the season.
“When you have 24 points to play for, a lot of things can happen. It’s my mentality – we take each game as it comes and try to finish as high up the table as we can.”
Bournemouth are safe and will have a real go at City, whose form has been horrendous on the road.
The way City are playing at the moment, it is hard to see them improving on that too much at the Vitality Stadium.