Kieran Richardson and Ciaran Clark are also doubtful with knocks.
Southampton pair Jose Fonte and Victor Wanyama are fit despite both requiring hospital treatment after respective head and rib injuries last weekend.
Charlie Austin and Florin Gardos remain out with knee problems.
MOTD COMMENTATOR’S NOTES
Mark Scott: “Eric Black feared post-relegation anarchy and while he was referring to matters on the pitch, that word pretty much sums up events off it since the inevitable was confirmed.
“The captain has been called ‘selfish’ and ‘insensitive’, two respected board members have walked out following a row with the owner and their longest-serving player has been suspended for the second time this month.
“Southampton’s European hopes might have faded a little, but bettering last season’s record Premier League points total is still a possibility and the biggest concern for Saints fans is whether they can get Ronald Koeman to extend his contract.
Aston Villa caretaker manager Eric Black on Jonas Okore: “I don’t want people who don’t want to be at Aston Villa and playing at Aston Villa, certainly under the circumstances, and the Bournemouth game was a massive game for us.
“So he has gone to the Under-21s and that’s what happens.”
Southampton manager Ronald Koeman: “It [European qualification] is always possible [but] it is very difficult because [there] is a gap of four or five points between us and Liverpool and West Ham.
“That is why we are still focused and concentrated because it is still not the end of the season and I don’t like to end the season in a bad way.
“We still have good games to play and this Saturday is a difficult one for several reasons. They are already relegated, it will be a difficult atmosphere in the stadium.”
Villa were officially relegated last week but it will take until the season ends for them to be put out of their misery.
Saints have had to get used to seeing players leave at the end of each season but their recruitment has been very good to make up for that.
They might also be a bit worried about hanging on to their manager Ronald Koeman this summer too.