Forgotten man Wilshere broke his left leg in a collision with Tottenham’s Harry Kane in April while on loan at Bournemouth.
He will make his first appearance for the Gunners in 13 months against Cologne in the Europa League.
And Wenger insists the England star is on his way back to his best after overcoming the trauma of the latest in a string of injuries.
The Arsenal boss said: “We are all different. Some just come back like nothing happened to them, some are traumatised for their whole life.
“It is like you have a car accident, some don’t want to drive any more and some take the car and go on again. It is very different and depends on the personality of people.