The Premier League fixtures are out for the 2016-17 season — here are five to watch for Tottenham.

Every home match will be significant for Tottenham next season, as they bid farewell to White Hart Lane, their home since 1899. They begin their campaign away at Everton and end it away to Hull City, after playing their final home game against Manchester United on May 13.

(A) – November. 26, 2016
(H) – Jan. 2, 2017

Tottenham’s 2-2 draw at Stamford Bridge in May was fraught with animosity — Mousa Dembele is serving a six-match ban, and Spurs received a Premier League record nine yellow cards — suggesting the start of a newly vitriolic rivalry between the pair, similar to Arsenal versus Manchester United in the late ’90s and early ’00s. Danny Rose said this week: “That is why I play football, games like that. To feel the hatred from the Chelsea fans and their players beforehand. It was amazing. That’s now the first fixture we’re looking at next season: Chelsea at home and Chelsea away.” Spurs still haven’t won at Stamford Bridge since 1990.

(A) – Nov. 5, 2016
(H) – April 29, 2017

Arsenal’s visit is already Tottenham’s biggest match of every season but as the penultimate game at White Hart Lane and the fourth to last of the season, it promises to be one of the most emotionally-charged occasions in the stadium’s 117-year history. Mauricio Pochettino is yet to lose a North London derby in the league but Spurs will feel they should have won both last season after squandering leads home and away, helping Arsenal to finish above them for the 21st consecutive season. Both games, particularly the second, could have a significant bearing on Champions League qualification or the title race.

West Ham
(H) – Nov. 19, 2016
(A) May 6, 2017

Tottenham’s visit has always been West Ham’s “Cup final” — according to Spurs fans, at least — but the Hammers’ improvement under Slaven Bilic has intensified a rivalry that was previously considered one-sided in North London. The mutual dislike runs from the boardroom to the terraces, and Spurs chairman Daniel Levy will be as desperate as any fan for victory at the Olympic Stadium after West Ham beat Spurs to a tax-payer-boosted deal for the stadium. The short trip across London is sandwiched between the final games at White Hart Lane — against Arsenal and Man United — in what is a very tough run-in for Tottenham.

Manchester City
(H) – Oct. 1, 2016
(A) – Jan. 21, 2017

Since City’s Qatari-windfall, Spurs and City have developed a competitive rivalry, based partly on a feeling in North London that Spurs’ would have enjoyed considerably more recent success had City not struck gold. Spurs beat City twice last season, humiliating them at White Hart Lane and ending their title hopes at the Etihad Stadium, and Pep Guardiola, whose appointment makes City the team to beat next season, will be seeking revenge.

Manchester United
(A) – Dec. 10, 2016
(H) – May 13, 2017

Spurs will look back on 117 years of history when they bid farewell to their world famous home in the final match at White Hart Lane on May, 13 2017. And who better to do it against than Jose Mourinho’s Manchester United, the most decorated club in Premier League and English football history? The occasion will be hugely emotional for Spurs fans but there’s every chance this could significant in the race for the top four or even the title, and the players will have to keep their cool.